Nicole Pinaire, Ph.D.
Assistant Professor in Biology
B.S. in Biomedical Engineering, Saint Louis University
Ph.D. in Molecular Biology and Cancer Biology, The University of Texas Graduate School of Biomedical Sciences at Houston
General Biology 1 and 2
Anatomy and Physiology 1 and 2
Senior Seminar: Research in Biology
Cellular and Molecular Biology
Special Topics: Bioengineering
Integrating the Concepts in Biology
Dr. Pinaire’s teaching focus is on molecular biology and general biology including botany, animal systems and anatomy and physiology.
Publications and professional presentation have included work on mechanisms of cancer cell migration and metastasis as well as tumor suppression studies.
Pinaire, NL and TJ McDonnell. Alterations in Cell Adhesion and Migration are Transcriptionally Regulated by the Tumor Suppressor, TP53. Innovative Minds in Prostate Cancer Today (IMPaCT). Orlando, FL. March 9-12, 2011 (mandatory submission for Grant PC07147).
Pinaire, N, P Johnson, N Chari, K Spurgers, T McDonnell. Novel Transcriptional Targets of p53 May Inhibit Cell Migration. American Association of Cancer Research 100th Annual Meeting. Denver, CO. April 18-22, 2009.
Chari NS, Pinaire NL, Thorpe L, Medeiros LJ, Routbort MJ, McDonnell TJ. The p53 tumor suppressor network in cancer and the therapeutic modulation of cell death. Apoptosis. 2009 Apr;14(4):336-47. Review.
Pinaire, NL, S Manduku, KB Spurgers, RE Meyn, TJ McDonnell. A Comprehensive and Global Genomic Assessment of p53-regulated Transcriptional Targets. American Association of Cancer Research 98th Annual Meeting. Los Angeles, CA. April 14-18, 2007.
Spurgers KB, Gold DL, Coombes KR, Bohnenstiehl NL, Mullins B, Meyn RE, Logothetis CJ, McDonnell TJ. Identification of cell cycle regulatory genes as principal targets of p53-mediated transcriptional repression. J Biol Chem. 2006 Sep 1;281(35):25134-42.
Spurgers KB, Chari NS, Bohnenstiehl NL, McDonnell TJ. Molecular mediators of cell death in multistep carcinogenesis: a path to targeted therapy. Cell Death Differ. 2006 Aug;13(8):1360-70.
Spurgers, K, G Rolle, N Bohnenstiehl, B Mullins, R Meyn, T McDonnell. Cell Cycle Regulatory Genes are Principal Targets of p53-dependent, RB-mediated Transcriptional Repression Following DNA Damage. American Association of Cancer Research 97th Annual Meeting. Washington, D.C. April 1-5, 2006.
Awards and Honors
Dr. Pinaire was awarded the HBU 2010-2011 Opal Goolsby Outstanding Teaching Award.
At HBU, Dr. Pinaire has served as a representative of COSM to the Faculty Assembly Executive Board and has served on the HBU Professional Development Committee.
Dr. Pinaire enjoys interacting with our students and giving them opportunities to learn and grow outside the classroom. As such, she serves a sponsor of HBU American Red Cross Society as well as co-sponsors the HBU Tri Beta Biological Honor Society. Dr. Pinaire is also co-chair of the Biology Honors Program.
To maintain her research interests, Dr. Pinaire has enjoyed collaborating with scientists at M.D. Anderson Cancer Center to study cell migration mechanisms.